Description

9-Chloro-7-(2-Chlorophenyl)-3,5-Dihydro-(1,2,4)Triazino(4,3-A)(1,4)Benzodiazepin-2(1H)-One is a high-purity, heterocyclic organic compound belonging to the triazino-benzodiazepine class, serving as a critical advanced pharmaceutical intermediate. Its complex fused-ring structure makes it a valuable building block for the synthesis of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. This compound is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of central nervous system (CNS) agents and other specialized medicinal chemistry applications.

Application

• Pharmaceutical Intermediate: Key precursor in the research and synthesis of novel benzodiazepine-derived therapeutic agents.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• CNS Drug Development: Serves as a building block for potential candidates targeting neurological and psychiatric disorders.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Reference Standard: Can be utilized as an analytical standard for quality control and method development in API manufacturing.
• Academic Research: Employed in university and institutional labs for studying heterocyclic chemistry and pharmacological mechanisms.

Basic Information

Product Name	9-Chloro-7-(2-Chlorophenyl)-3,5-Dihydro-(1,2,4)Triazino(4,3-A)(1,4)Benzodiazepin-2(1H)-One
CAS No.	49614-12-2
Molecular Formula	C₁₈H₁₂Cl₂N₄O
Molecular Weight	371.22 g/mol
Synonyms	9-Chloro-7-(2-chlorophenyl)-1,2,4-triazino[4,3-a][1,4]benzodiazepin-2(1H)-one; 9-Chloro-7-(o-chlorophenyl)-3,5-dihydro-1,2,4-triazino[4,3-a][1,4]benzodiazepin-2(1H)-one; 49614-12-2; Triazino(4,3-a)(1,4)benzodiazepin-2(1H)-one, 9-chloro-7-(2-chlorophenyl)-3,5-dihydro-; 9-Chloro-7-(2-chlorophenyl)-3,5-dihydro-1H-[1,2,4]triazino[4,3-a][1,4]benzodiazepin-2-one
EINECS	Contact for details

Quality Control

Our 9-Chloro-7-(2-Chlorophenyl)-3,5-Dihydro-(1,2,4)Triazino(4,3-A)(1,4)Benzodiazepin-2(1H)-One is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, and we support compliance with REACH and other relevant global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.