Description

2-Chloronicotinyl Chloride is a versatile and highly reactive chemical intermediate essential for advanced organic synthesis. Its bifunctional chlorinated pyridine structure makes it a critical building block for constructing complex molecules with precision. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and other therapeutic areas.
• Agrochemical Synthesis: Used in the manufacture of advanced pesticides, herbicides, and fungicides, where the nicotinyl moiety is integral to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organometallic catalysts used in cross-coupling reactions.
• Material Science Research: Employed in the development of functional polymers and advanced organic electronic materials.
• Custom Synthesis and Contract Manufacturing: A fundamental reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	2-Chloronicotinyl Chloride
CAS No.	49609-84-9
Molecular Formula	C6H3Cl2NO
Molecular Weight	176.00 g/mol
Synonyms	2-Chloropyridine-3-carbonyl Chloride; 3-Pyridinecarbonyl Chloride, 2-Chloro-; 2-Chloronicotinic Acid Chloride; 2-Chloro-3-pyridinecarbonyl chloride; 2-Chloro-3-chlorocarbonylpyridine; Nicotinoyl chloride, 2-chloro-; 2-Chloronicotinoyl Chloride
EINECS	Contact for details

Quality Control

Our 2-Chloronicotinyl Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.