Description

D-Glutamic Acid, 1,5-Bis(Phenylmethyl) Ester is a high-purity, protected derivative of the non-proteinogenic D-isomer of glutamic acid. This compound is a critical chiral building block and protecting group reagent in advanced organic synthesis, particularly for peptide and amino acid chemistry. It is essential for research and development laboratories, pharmaceutical intermediates, and fine chemical manufacturers requiring enantiomerically pure components.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of complex drug candidates, peptides, and bioactive molecules.
• Peptide Chemistry: Used as a protected D-glutamic acid residue in solid-phase and solution-phase peptide synthesis to prevent unwanted side reactions.
• Asymmetric Synthesis: Acts as a chiral auxiliary or starting material for the preparation of enantiomerically pure compounds in medicinal chemistry.
• Biochemical Research: Employed in studies of enzyme specificity, metabolic pathways, and the development of enzyme inhibitors.
• Fine Chemical Production: A precursor for specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Industrial R&D: Utilized in method development and discovery chemistry within university and corporate research settings.

Basic Information

Product Name	D-Glutamic Acid, 1,5-Bis(Phenylmethyl) Ester
CAS No.	47376-46-5
Molecular Formula	C19H21NO4
Molecular Weight	327.38 g/mol
Synonyms	D-Glutamic Acid α,γ-Dibenzyl Ester; Dibenzyl D-glutamate; (R)-2-Amino-1,5-dibenzyl pentanedioate; D-Glutamic Acid Dibenzyl Ester; Benzyl D-glutamate; D-Glutamic Acid Dibenzyl Ester Hydrochloride (salt form); D-2-Aminopentanedioic Acid 1,5-Dibenzyl Ester
EINECS	Contact for details

Quality Control

Our D-Glutamic Acid, 1,5-Bis(Phenylmethyl) Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets exacting standards for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.