Description

2-Acetamido-5-Chloropyridine is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its dual functional groups, which enable precise molecular modifications for creating complex, high-value compounds. This intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the chloropyridine moiety contributes to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or molecular components for OLEDs.
• Custom Synthesis and Contract Manufacturing: A fundamental substrate for custom chemical synthesis services catering to R&D and pilot-scale production.
• Academic and Industrial Research: A valuable tool for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Item	Details
Product Name	2-Acetamido-5-Chloropyridine
CAS No.	45965-30-8
Molecular Formula	C7H7ClN2O
Molecular Weight	170.60 g/mol
Synonyms	N-(5-Chloropyridin-2-yl)acetamide; 5-Chloro-2-acetamidopyridine; 2-Acetylamino-5-chloropyridine; 2-Acetamido-5-chloro-pyridine; Acetamide, N-(5-chloro-2-pyridinyl)-; 5-Chloro-2-pyridinylacetamide
EINECS	Contact for details

Quality Control

Our 2-Acetamido-5-Chloropyridine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical parameters. Our quality commitment ensures the material meets the exacting standards required for research and cGMP-intermediate synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.