Description

2-Amino-6-Chloropyridine is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both an amino group and a chloro substituent on the pyridine ring, makes it a highly valuable intermediate for constructing complex molecular architectures. This compound is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and insecticides, where the pyridine core contributes to biological activity.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing nitrogen-containing ligands used in transition metal catalysis.
• Material Science: Building block for creating functional polymers, liquid crystals, and organic electronic materials.
• Chemical Research: A valuable reagent for heterocyclic chemistry research, enabling nucleophilic substitution and cross-coupling reactions.
• Dye and Pigment Industry: Intermediate in the production of specialized dyes and pigments.

Basic Information

Product Name	2-Amino-6-Chloropyridine
CAS No.	45644-21-1
Molecular Formula	C5H5ClN2
Molecular Weight	128.56 g/mol
Synonyms	6-Chloro-2-pyridinamine; 6-Chloro-2-aminopyridine; 2-Amino-6-chloropyridine; 6-Chloropyridin-2-amine; 2-Pyridinamine, 6-chloro-; 6-Chloro-2-aminopyridine; 2-Amino-6-chloro-pyridine; 6-Chloro-2-pyridylamine
EINECS	Contact for details

Quality Control

Our 2-Amino-6-Chloropyridine is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of our global B2B clients. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment supports applications in regulated environments, and we can discuss compliance with specific standards such as ICH guidelines upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.