Description

(R)-2-Acetoxy-3-Methylbutanoic Acid is a high-purity chiral building block and synthetic intermediate of significant importance in fine chemical synthesis. Its value lies in its defined stereochemistry, which is critical for producing optically active compounds with specific biological activities. This product is essential for research and development laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of protease inhibitors, antiviral drugs, and other therapeutics where stereochemical purity is paramount.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides, where the specific enantiomer can lead to enhanced efficacy and reduced environmental impact.
• Asymmetric Catalysis & Ligand Synthesis: Serves as a precursor for chiral ligands and catalysts used in enantioselective synthesis, enabling the production of single-enantiomer compounds.
• Flavor and Fragrance Industry: Potential intermediate for the synthesis of complex, naturally-derived flavor compounds and aroma chemicals requiring specific stereochemistry.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and for exploring new reaction pathways in medicinal chemistry.
• Peptide Mimetics: Used in the construction of peptidomimetics and modified amino acid derivatives for drug discovery programs.

Basic Information

Product Name	(R)-2-Acetoxy-3-Methylbutanoic Acid
CAS No.	44976-78-5
Molecular Formula	C7H12O4
Molecular Weight	160.17 g/mol
Synonyms	(R)-O-Acetyl-3-methyl-D-lactic acid; (R)-2-(Acetyloxy)-3-methylbutanoic acid; (R)-α-Acetoxyisovaleric acid; D-2-Acetoxy-3-methylbutyric acid; (2R)-2-Acetoxy-3-methylbutanoic acid; (R)-O-Acetyl-3-methyl-D-2-hydroxybutyric acid; (R)-2-Acetoxy-3-methylbutyric acid
EINECS	Contact for details

Quality Control

Our (R)-2-Acetoxy-3-Methylbutanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and enantiomeric purity, meeting the stringent requirements of advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.