Description

(S)-Isobutyl 2-Aminopropanoate is a chiral, non-natural amino acid ester derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and high-purity building block for the preparation of pharmaceuticals, peptides, and fine chemicals, where stereochemical control is critical. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and chiral intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in protease inhibitor and peptidomimetic drug development.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis as a protected amino acid derivative to introduce the L-alanine moiety with an isobutyl ester protecting group.
• Agrochemical Research: Serves as a precursor in the design and synthesis of novel chiral herbicides, fungicides, and plant growth regulators.
• Asymmetric Catalysis: Employed as a ligand precursor or a chiral auxiliary in asymmetric synthesis to induce enantioselectivity.
• Flavor & Fragrance Industry: Potential use in the synthesis of complex, chiral flavor compounds and aroma chemicals.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry, medicinal chemistry, and chemical biology.

Basic Information

Product Name	(S)-Isobutyl 2-Aminopropanoate
CAS No.	44921-72-4
Molecular Formula	C7H15NO2
Molecular Weight	145.20 g/mol
Synonyms	L-Alanine isobutyl ester; (S)-2-Aminopropanoic acid isobutyl ester; Isobutyl L-alaninate; (S)-2-Amino-propionic acid isobutyl ester; L-2-Aminopropionic acid isobutyl ester; (S)-Isobutyl alaninate; Alanine, isobutyl ester, L-; (S)-Isobutyl 2-aminopropionate
EINECS	Contact for details

Quality Control

Our (S)-Isobutyl 2-Aminopropanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with high-grade specifications for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee reproducible quality and enantiomeric excess for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and oxidizable nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.