Description

1-Isocyano-2-Methoxyethane is a versatile isocyanide building block used in organic synthesis and pharmaceutical research. This compound is valued for its reactivity, particularly in multi-component reactions and as a ligand precursor in catalysis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of heterocyclic compounds and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides.
• Multi-Component Reactions (MCRs): Essential reagent in Ugi, Passerini, and related isocyanide-based reactions for rapid library generation.
• Catalysis: Serves as a precursor for N-heterocyclic carbene (NHC) ligands and other organocatalysts.
• Material Science: Employed in the synthesis of functional polymers and specialty chemicals.
• Chemical Biology: Useful as a bioorthogonal labeling agent and probe in bioconjugation strategies.

Basic Information

Product Name	1-Isocyano-2-Methoxyethane
CAS No.	43219-50-7
Molecular Formula	C4H7NO
Molecular Weight	85.10 g/mol
Synonyms	2-Methoxyethyl isocyanide; Isocyanomethoxyethane; Methoxyethyl isocyanide; 2-Isocyanoethyl methyl ether; 2-Methoxyethyl isonitrile; NSC 163063
EINECS	Contact for details

Quality Control

Our 1-Isocyano-2-Methoxyethane is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at room temperature (15-25°C). Due to its highly volatile and light-sensitive nature, containers should be kept sealed and handled under an inert atmosphere when possible to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.