Description

Octanedioic Acid Bis(Trimethylsilyl) Ester is a high-purity silylating reagent and synthetic intermediate derived from suberic acid. This compound is valued for its role in protecting hydroxyl groups and facilitating derivatization for analytical chemistry, particularly in gas chromatography. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors who require reliable, high-quality intermediates for complex synthesis and sensitive analytical procedures.

Application

• Derivatization Agent for GC Analysis: Used to convert polar, non-volatile compounds (like carboxylic acids, alcohols) into volatile trimethylsilyl (TMS) derivatives for gas chromatography (GC) and GC-MS analysis.
• Pharmaceutical Intermediate: Serves as a protected form of suberic acid in multi-step organic synthesis for active pharmaceutical ingredients (APIs) and drug discovery.
• Polymer & Material Science: Acts as a monomer or modifying agent in the synthesis of specialty polyesters, polyamides, and silicon-containing polymers.
• Agrochemical Synthesis: Employed as a building block in the production of advanced crop protection agents and plant growth regulators.
• Crosslinking Agent: Utilized in the formulation of advanced coatings, adhesives, and sealants where specific chemical resistance or properties are required.
• Laboratory Reagent: A key reagent for hydroxyl group protection/deprotection strategies in complex organic synthesis workflows.

Basic Information

Item	Details
Product Name	Octanedioic Acid Bis(Trimethylsilyl) Ester
CAS No.	43199-48-0
Molecular Formula	C14H32O4Si2
Molecular Weight	320.58 g/mol
Synonyms	Suberic Acid Bis(trimethylsilyl) Ester; Bis(trimethylsilyl) Suberate; Suberic Acid Bis(TMS) Ester; TMS Suberate; Bis(trimethylsilyl) Octanedioate; Octanedioic Acid Di(trimethylsilyl) Ester; 1,8-Bis(trimethylsiloxy)-1,8-octanedione (alternative representation); Suberic Acid TMS Derivative
EINECS	Contact for details

Quality Control

Every batch of Octanedioic Acid Bis(Trimethylsilyl) Ester is manufactured under strict quality management protocols. We ensure product integrity through comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR). A Certificate of Analysis (COA) detailing purity, identity, and specific parameters is provided with each shipment to guarantee compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can compromise product quality. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.