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1-(Trimethylsilyl)-1H-Benzotriazole CAS NO 43183-36-4


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CAS No.:43183-36-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-(Trimethylsilyl)-1H-Benzotriazole is a versatile organosilicon-protected benzotriazole derivative, primarily used as a key synthetic intermediate and protecting group reagent. Its value lies in its ability to act as a masked benzotriazole unit, facilitating complex organic transformations in moisture-sensitive environments. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for sophisticated synthesis.

Application

  • Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring silyl-protected nitrogen heterocycles.
  • Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the trimethylsilyl group offers temporary protection during multi-step synthesis.
  • Organometallic Chemistry: Acts as a ligand precursor or a reagent in the preparation of metal-organic complexes and catalysts.
  • Polymer & Material Science: Employed in the development of specialty polymers, resins, and silicon-containing advanced materials.
  • Organic Synthesis Reagent: Functions as a protecting group for benzotriazole, enabling selective reactions in complex molecular constructions.
  • Research & Development: A valuable tool for academic and industrial R&D laboratories exploring new synthetic methodologies.

Basic Information

Product Name 1-(Trimethylsilyl)-1H-Benzotriazole
CAS No. 43183-36-4
Molecular Formula C9H13N3Si
Molecular Weight 191.31 g/mol
Synonyms 1-(Trimethylsilyl)benzotriazole; Benzotriazole, 1-(trimethylsilyl)-; 1H-Benzotriazole, 1-(trimethylsilyl)-; TMS-Bt; N-Trimethylsilylbenzotriazole; 1-Trimethylsilylbenzotriazole; 1-TMS-benzotriazole; Benzotriazole-1-trimethylsilyl
EINECS Contact for details

Quality Control

Our 1-(Trimethylsilyl)-1H-Benzotriazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from moisture and direct light exposure to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Melting Point Contact for details
Loss on Drying ≤ 0.5%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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