Description

Trimethyl Orthobutyrate is a specialized organic ester, also known as trimethyl butyrate, with the CAS number 43083-12-1. This compound serves as a versatile alkylating agent and protected intermediate in advanced organic synthesis, enabling precise molecular construction. It is primarily utilized by manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for producing active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing butyrate ester groups.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators requiring specific ester functionalities.
• Flavor and Fragrance Ingredient: Acts as a precursor for esters that contribute fruity notes in flavor compositions and fragrance formulations.
• Polymer Modification: Employed as a transesterification agent or monomer in the production of specialty polymers and coatings.
• Organic Synthesis Reagent: Serves as a protecting group for carboxylic acids or as a source of the methoxycarbonyl group in multi-step synthetic routes.
• Chemical Research & Development: A valuable reagent in laboratory-scale R&D for exploring new synthetic methodologies and compound libraries.

Basic Information

Product Name	Trimethyl Orthobutyrate
CAS No.	43083-12-1
Molecular Formula	C7H16O3
Molecular Weight	148.20 g/mol
Synonyms	Trimethyl Butyrate; Butyric Acid Trimethyl Ester; Methyl Butyrate (Trimethyl); Orthobutyric Acid Trimethyl Ester; Trimethoxybutane; Butanoic Acid, Trimethyl Ester; TMOB; 1,1,1-Trimethoxybutane
EINECS	256-104-5

Quality Control

Our Trimethyl Orthobutyrate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for sensitive synthetic applications. Certificates of Analysis (COA) documenting purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (20°C)	1.390 - 1.400
Density (20°C)	0.92 - 0.96 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.