Description

Dimethyl 4-(2-Chlorophenyl)-2,6-Dimethyl-1,4-Dihydropyridine-3,5-Dicarboxylate is a high-purity dihydropyridine derivative, a key structural motif in medicinal chemistry. This compound is valued for its role as a versatile synthetic intermediate and a critical scaffold for developing biologically active molecules. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of calcium channel modulators and other therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of 1,4-dihydropyridine-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold for designing and synthesizing novel compounds with potential cardiovascular, neurological, or other therapeutic activities.
• Chemical Reference Standard: Employed as an analytical standard in quality control (QC) and research & development (R&D) laboratories for method development and validation.
• Organic Synthesis: Acts as a versatile intermediate in complex organic synthesis for constructing heterocyclic compounds with specific stereochemistry.

Basic Information

Product Name	Dimethyl 4-(2-Chlorophenyl)-2,6-Dimethyl-1,4-Dihydropyridine-3,5-Dicarboxylate
CAS No.	43067-01-2
Molecular Formula	C17H18ClNO4
Molecular Weight	335.78 g/mol
Synonyms	Dimethyl 2,6-Dimethyl-4-(2-chlorophenyl)-1,4-dihydropyridine-3,5-dicarboxylate; 1,4-Dihydro-2,6-dimethyl-4-(2-chlorophenyl)-3,5-pyridinedicarboxylic Acid Dimethyl Ester; 4-(2-Chlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylic Acid Dimethyl Ester; 2-Chloro-DHP; 2'-Chloro-DHP; Hantzsch Ester Derivative
EINECS	Contact for details

Quality Control

Our Dimethyl 4-(2-Chlorophenyl)-2,6-Dimethyl-1,4-Dihydropyridine-3,5-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed batch-specific data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.