Description

2-Bromopyridine is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its primary value lies in its reactivity as an electrophile, enabling efficient cross-coupling reactions and functional group transformations essential for pharmaceutical and agrochemical development. This high-purity intermediate is indispensable for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to construct complex heterocyclic architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs containing pyridine or bipyridine cores.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides where the bromopyridine moiety imparts specific biological activity.
• Ligand & Catalyst Preparation: Serves as a starting material for synthesizing sophisticated ligands used in homogeneous catalysis, such as in Suzuki-Miyaura or Buchwald-Hartwig cross-coupling reactions.
• Material Science: Building block for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: A fundamental reagent in academic and industrial R&D for exploring new synthetic methodologies and creating novel chemical entities.

Basic Information

Product Name	2-Bromopyridine
CAS No.	42981-41-9
Molecular Formula	C5H4BrN
Molecular Weight	157.99 g/mol
Synonyms	2-Bromopyridine; α-Bromopyridine; Pyridine, 2-bromo-; o-Bromopyridine; 2-Pyridyl bromide; Bromopyridine; NSC 6055
EINECS	256-025-5

Quality Control

Our 2-Bromopyridine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Total impurities ≤ 2.0%
Density (at 20°C)	~1.657 g/cm³
Boiling Point	~193-194 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.