Description

5-Bromo-2-Chloro-4,6-Dimethylnicotinonitrile is a high-purity, multi-functional heterocyclic building block of significant commercial importance. Its unique halogenated and nitrile-substituted pyridine structure makes it a critical intermediate for the synthesis of complex molecules in advanced research and development. This compound is primarily sought after by pharmaceutical, agrochemical, and specialty chemical manufacturers for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides due to its bioactive scaffold.
• Material Science Research: Serves as a precursor for designing functional organic materials, including liquid crystals and organic semiconductors.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for biochemical and diagnostic research.
• Custom Synthesis & Contract Manufacturing: An essential building block for fine chemical and CDMO (Contract Development and Manufacturing Organization) services.

Basic Information

Product Name	5-Bromo-2-Chloro-4,6-Dimethylnicotinonitrile
CAS No.	42951-71-3
Molecular Formula	C8H6BrClN2
Molecular Weight	245.50 g/mol
Synonyms	5-Bromo-2-chloro-4,6-dimethyl-3-pyridinecarbonitrile; 5-Bromo-2-chloro-4,6-dimethylnicotinonitrile; 3-Cyano-5-bromo-2-chloro-4,6-dimethylpyridine; 2-Chloro-5-bromo-4,6-dimethyl-3-cyanopyridine; 4,6-Dimethyl-5-bromo-2-chloro-3-cyanopyridine; 42951-71-3; 5-Bromo-2-chloro-4,6-lutidine-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Chloro-4,6-Dimethylnicotinonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.