Description

Lopirazepam is a benzodiazepine derivative of significant interest in pharmaceutical research and development. Its primary value lies in its potential as a key intermediate or active pharmaceutical ingredient (API) for the synthesis of novel therapeutic agents targeting the central nervous system. This compound is essential for research organizations, pharmaceutical manufacturers, and chemical suppliers focused on developing new anxiolytic, sedative, or anticonvulsant medications.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of advanced benzodiazepine-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in preclinical and clinical research to study structure-activity relationships (SAR) and develop new neuropharmacological compounds.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Chemical Synthesis: Acts as a precursor for the preparation of more complex molecules in medicinal chemistry programs.

Basic Information

Item	Details
Product Name	Lopirazepam
CAS No.	42863-81-0
Molecular Formula	C₁₆H₁₂ClN₃O₂
Molecular Weight	313.74 g/mol
Synonyms	7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-1-methyl-2H-1,4-benzodiazepin-2-one; Lopirazepamum; Lopirazepam (INN); 1-Methyl-7-chloro-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one; Ro 05-5807
EINECS	Contact for details

Quality Control

Our Lopirazepam is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via advanced techniques like HPLC and GC. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.