Description

2,4-Dichloro-6-Picoline is a halogenated pyridine derivative, a versatile and high-value chemical intermediate prized for its unique reactivity. Its molecular structure, featuring chlorine atoms at the 2 and 4 positions of the pyridine ring, makes it a critical building block for synthesizing complex molecules in advanced research and industrial manufacturing. This compound is essential for pharmaceutical chemists, agrochemical researchers, and material scientists developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infective agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the dichloropicoline moiety contributes to biological activity.
• Ligand and Catalyst Preparation: Serves as a starting material for creating specialized nitrogen-containing ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of advanced polymers, liquid crystals, and electronic materials that require functionalized pyridine units.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic aromatic substitution to introduce the 2,4-dichloro-6-picolinyl group into more complex structures.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry research in both academic and industrial R&D laboratories.

Basic Information

Product Name	2,4-Dichloro-6-Picoline
CAS No.	42779-56-6
Molecular Formula	C6H5Cl2N
Molecular Weight	162.02 g/mol
Synonyms	2,4-Dichloro-6-methylpyridine; 6-Methyl-2,4-dichloropyridine; 2,4-Dichloro-6-picoline; 2,4-Dichloro-6-methylpyridine; 2,4-Dichloro-6-picoline; 6-Picoline, 2,4-dichloro-; 2,4-Dichloro-6-methylpyridine
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-6-Picoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.