Description

3,4-Difluorophenyl Isocyanate is a specialized aromatic isocyanate monomer characterized by its reactive isocyanate (-NCO) group and difluorinated phenyl ring. This compound is a critical building block in the synthesis of advanced materials, where its fluorine substituents impart unique chemical stability and physical properties to the final products. It is primarily sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for constructing ureas, carbamates, and other high-value heterocycles.

Application

• Pharmaceutical Intermediates: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and other small-molecule therapeutics where the difluorophenyl moiety enhances metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where its structure contributes to improved efficacy and environmental profile.
• Polymer & Material Science: Serves as a monomer for synthesizing polyurethanes and polyurea coatings with enhanced chemical resistance, weatherability, and thermal stability for high-performance applications.
• Liquid Crystal & OLED Materials: Employed in the synthesis of fluorinated components for electronic display materials, contributing to better charge transport and device longevity.
• Cross-linking Agent: Functions as an efficient cross-linker for resins and polymers, improving mechanical strength and durability in composite materials.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D in organic synthesis, facilitating the exploration of novel fluorinated compounds.

Basic Information

Product Name	3,4-Difluorophenyl Isocyanate
CAS No.	42601-04-7
Molecular Formula	C7H3F2NO
Molecular Weight	155.10 g/mol
Synonyms	1-Isocyanato-3,4-difluorobenzene; 3,4-Difluorophenylisocyanate; 3,4-Difluorobenzene Isocyanate; m,p-Difluorophenyl Isocyanate; (3,4-Difluorophenyl)carbimidoic Acid; NSC 406916; 3,4-DFPI
EINECS	Contact for details

Quality Control

Our 3,4-Difluorophenyl Isocyanate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at temperatures between 2°C and 8°C (refrigerated) or as specified on the label. This material is hygroscopic (moisture-sensitive) and light-sensitive; exposure to moisture or prolonged light can lead to degradation and polymerization. Keep away from heat, sparks, open flames, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Specific Gravity (20°C)	~1.35 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.