Description

1-Isocyano-3-Methoxy-Propane is a versatile organic building block characterized by its reactive isocyano group and methoxy-functionalized alkyl chain. This compound is valued for its role as a key intermediate in the synthesis of heterocyclic compounds and functionalized polymers. It is primarily utilized by research and development chemists, as well as process development teams, in the pharmaceutical, agrochemical, and specialty chemical industries. Its high volatility necessitates careful handling and storage to maintain purity and reactivity.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, where its reactive group enables the introduction of specific functional moieties.
• Ligand and Catalyst Development: Employed in the preparation of specialized isocyanide-based ligands for transition metal catalysis and organocatalysis.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for creating polymers with tailored properties, such as adhesives or coatings.
• Organic Synthesis Reagent: A valuable reagent in multi-component reactions (e.g., Ugi, Passerini) for the efficient construction of complex molecular architectures in research settings.
• Chemical Biology Probes: Utilized in the synthesis of probes and tags for studying biological processes due to its bio-conjugation capability.

Basic Information

Product Name	1-Isocyano-3-Methoxy-Propane
CAS No.	42563-58-6
Molecular Formula	C5H9NO
Molecular Weight	99.13 g/mol
Synonyms	3-Methoxypropyl isocyanide; 3-Methoxypropyl isonitrile; 1-Isocyano-3-methoxypropane; 3-Methoxy-1-isocyanopropane; 3-Methoxypropylisonitrile; NSC 163058; (3-Methoxypropyl)isocyanide; 3-Methoxypropane isocyanide
EINECS	Contact for details

Quality Control

Our 1-Isocyano-3-Methoxy-Propane is produced under stringent quality management protocols. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at temperatures between 2°C and 8°C (refrigerated) to minimize volatility and degradation. Keep away from heat, sparks, and open flames. Due to its highly volatile nature, containers must be kept tightly sealed when not in use and handled in a fume hood.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.