Description

4β-[3-(2-Chloroethyl)-3-Nitrosoureido]-1α-Cyclohexanecarboxylic Acid is a specialized nitrosourea derivative with a unique cyclohexanecarboxylic acid backbone. This compound is of significant interest in advanced pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in oncology and targeted drug discovery programs. The compound's specific structure offers a valuable building block for creating molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel chemotherapeutic agents and targeted cancer therapies.
• Biochemical Research: Used as a specialized reagent in studies involving alkylating agents and their mechanisms of action on DNA.
• Medicinal Chemistry: Serves as a critical scaffold for structure-activity relationship (SAR) studies to develop new drug candidates.
• Oncology Research: Employed in the development of experimental nitrosourea-based compounds for evaluating antitumor efficacy.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	4β-[3-(2-Chloroethyl)-3-Nitrosoureido]-1α-Cyclohexanecarboxylic Acid
CAS No.	42558-94-1
Molecular Formula	C10H17ClN4O4
Molecular Weight	292.72 g/mol
Synonyms	1α-Cyclohexanecarboxylic acid, 4β-[3-(2-chloroethyl)-3-nitrosoureido]-; 4β-[3-(2-Chloroethyl)-3-nitrosoureido]-1α-cyclohexanecarboxylic acid; 1α-Cyclohexanecarboxylic acid, 4β-[[(2-chloroethyl)nitrosoamino]carbonyl]amino]-; Nitrosourea CCNU derivative; Cyclohexanecarboxylic acid nitrosourea analog; Lomustine related compound; 1α,4β-Cyclohexanedicarboxylic acid derivative; Chloroethylnitrosourea-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4β-[3-(2-Chloroethyl)-3-Nitrosoureido]-1α-Cyclohexanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical quality attributes. We support compliance with relevant guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.