Description

1-Acetylspiro[Indoline-3,1'-Cyclopentane] is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic molecular architecture. This compound is of significant commercial importance for its role as a key building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, including central nervous system (CNS) drugs and other specialized active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates, especially those targeting neurological pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Organic Synthesis Building Block: Employed in the construction of complex spirocyclic and heterocyclic compounds due to its rigid, three-dimensional structure.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for studying synthetic methodologies and developing new catalytic reactions involving spiro compounds.

Basic Information

Product Name	1-Acetylspiro[Indoline-3,1'-Cyclopentane]
CAS No.	42540-56-7
Molecular Formula	C15H17NO
Molecular Weight	227.30 g/mol
Synonyms	1-Acetylspiro[indoline-3,1'-cyclopentane]; 1'-Acetylspiro[cyclopentane-1,3'-indoline]; N-Acetylspiro[indoline-3,1'-cyclopentane]; Spiro[indoline-3,1'-cyclopentane]-1-carbaldehyde (related); 1-Acetyl-1,3-dihydrospiro[indene-2,1'-cyclopentane] (isomer); 42540-56-7; N-Acetyl-1-azaspiro[4.4]nonane-2,8-dione (precursor); Contact for additional aliases.
EINECS	Contact for details

Quality Control

Our 1-Acetylspiro[Indoline-3,1'-Cyclopentane] is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical research and development. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with the standards expected by GMP-oriented facilities and global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.