Description

[R,(+)]-2-Chloropropionic Acid Ethyl Ester is a high-purity chiral building block and intermediate of significant importance in asymmetric synthesis. Its defined stereochemistry makes it a valuable precursor for the production of enantiomerically pure pharmaceuticals and agrochemicals. This compound is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and advanced material sectors.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A key starting material for the preparation of enantiopure active pharmaceutical ingredients (APIs), particularly those containing a chiral α-carbon center.
• Agrochemical Production: Used in the synthesis of optically active herbicides, pesticides, and plant growth regulators where biological activity is stereospecific.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric catalysis.
• Fine Chemical and Flavor/Fragrance Intermediate: Employed in the multi-step synthesis of complex, high-value specialty chemicals and aroma compounds.
• Academic and Industrial R&D: A critical reagent for methodological development in organic chemistry and process optimization studies.

Basic Information

Product Name	[R,(+)]-2-Chloropropionic Acid Ethyl Ester
CAS No.	42411-39-2
Molecular Formula	C5H9ClO2
Molecular Weight	136.58 g/mol
Synonyms	(R)-(+)-Ethyl 2-Chloropropionate; (R)-Ethyl 2-Chloropropanoate; D-(+)-2-Chloropropionic Acid Ethyl Ester; (R)-2-Chloropropionic Acid Ethyl Ester; Ethyl (R)-2-Chloropropionate; (+)-Ethyl 2-Chloropropionate; (R)-α-Chloropropionic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our [R,(+)]-2-Chloropropionic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC or GC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC/GC)	≥ 99.0% ee
Specific Rotation [α]D20	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.