Description

Cyclopropaneacetic Acid, A-Cyano-, Ethyl Ester is a versatile and high-value synthetic intermediate characterized by its reactive cyano and ester functional groups attached to a strained cyclopropane ring. This unique molecular architecture makes it a critical building block for the synthesis of complex pharmaceutical compounds and advanced agrochemicals. It is primarily sought after by research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing cyclopropane motifs, which are valuable in drug discovery for metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the cyclopropane ring can contribute to biological activity and environmental persistence.
• Fine Chemical Manufacturing: Serves as a specialized building block for creating complex molecules used in flavors, fragrances, and functional materials.
• Organic Synthesis Research: Employed in academic and industrial R&D for methodology development, cyclopropanation studies, and the construction of stereochemically complex targets.
• Peptidomimetic Chemistry: The cyano and ester groups make it a useful synthon for introducing non-natural amino acid analogs into peptide chains.

Basic Information

Product Name	Cyclopropaneacetic Acid, A-Cyano-, Ethyl Ester
CAS No.	42392-67-6
Molecular Formula	C8H11NO2
Molecular Weight	153.18 g/mol
Synonyms	Ethyl 2-Cyanocyclopropaneacetate; 2-Cyanocyclopropaneacetic Acid Ethyl Ester; Ethyl (2-Cyanocyclopropyl)acetate; Cyclopropaneacetic acid, 2-cyano-, ethyl ester; Ethyl 2-cyanocyclopropanecarboxylate (common misnomer); NSC 334044; A-Cyano-cyclopropaneacetic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Cyclopropaneacetic Acid, A-Cyano-, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically by GC or HPLC), identity confirmation (by IR, NMR), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and organic solvents. Recommended storage temperature is 2-8°C for long-term stability. The container must be kept tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Typical 98.5%)
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.450 - 1.460
Density (g/mL at 20°C)	1.05 - 1.15

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.