Description

n-tert-Butoxycarbonyl-L-Tryptophanpentachlorophenylester is a specialized protected amino acid derivative, specifically an activated ester of Boc-L-Tryptophan. This compound matters as a crucial building block in solid-phase peptide synthesis (SPPS), enabling the controlled and efficient incorporation of the tryptophan residue into complex peptide chains. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers developing therapeutic peptides, bioactive probes, and novel peptidomimetics. Its design offers enhanced stability and reactivity for demanding synthetic applications.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the automated, sequential assembly of peptides containing tryptophan.
• Pharmaceutical Research: Synthesis of peptide-based drug candidates, hormones, and diagnostic agents.
• Bioconjugation: Used to label proteins, antibodies, or other biomolecules with tryptophan-derived tags or probes.
• Organic Synthesis: Serves as a protected and activated reagent for the introduction of the indole side chain in complex organic molecules.
• Combinatorial Chemistry: Building block for creating diverse peptide libraries for high-throughput screening.
• Academic Research: Tool compound for studying peptide structure-activity relationships (SAR) and enzyme-substrate interactions.

Basic Information

Item	Detail
Product Name	n-tert-Butoxycarbonyl-L-Tryptophanpentachlorophenylester
CAS No.	42290-63-1
Molecular Formula	C24H23Cl5N2O4
Molecular Weight	564.72 g/mol
Synonyms	Boc-L-Trp-OPcp; Boc-L-Tryptophan pentachlorophenyl ester; Boc-Trp-OPcp; N-Boc-L-tryptophan pentachlorophenyl ester; N-(tert-Butoxycarbonyl)-L-tryptophan pentachlorophenyl ester; L-Tryptophan, N-[(1,1-dimethylethoxy)carbonyl]-, pentachlorophenyl ester; (S)-2-((tert-Butoxycarbonyl)amino)-3-(1H-indol-3-yl)propanoic acid pentachlorophenyl ester
EINECS	Contact for details

Quality Control

Our n-tert-Butoxycarbonyl-L-Tryptophanpentachlorophenylester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis to confirm enantiomeric integrity, and spectroscopic identification (NMR, IR). Certificates of Analysis (COA) with detailed chromatograms and full analytical data are provided to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This material is hygroscopic (moisture-sensitive); ensure containers are sealed under inert atmosphere or with desiccant to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.