Description

Oxilorphan is a potent and selective opioid receptor antagonist of significant interest in pharmacological research and development. Its primary value lies in its ability to modulate opioid pathways, making it a critical compound for studying addiction mechanisms, developing new therapeutic agents, and exploring neurochemical interactions. This high-purity chemical is essential for pharmaceutical R&D laboratories, academic institutions, and biotechnology companies focused on central nervous system (CNS) drug discovery and advanced neuropharmacology.

Application

• Pharmacological Research: A key reference standard and tool compound for investigating opioid receptor (mu, kappa, delta) binding affinity, selectivity, and functional activity.
• Drug Discovery & Development: Used as a lead compound or intermediate in the synthesis and screening of novel opioid antagonists and mixed agonist-antagonists for therapeutic applications.
• Neuroscience Studies: Employed in preclinical studies to understand the neurobiology of addiction, pain modulation, and reward pathways.
• Biochemical Assay Development: Serves as a critical component in developing and validating high-throughput screening (HTS) assays for opioid receptor targets.
• Reference Material: Used as a certified reference material (CRM) or analytical standard in quality control laboratories for method development and validation.
• Academic Research: A vital reagent for university and institutional research projects exploring opioid system physiology and pharmacology.

Basic Information

Product Name	Oxilorphan
CAS No.	42281-59-4
Molecular Formula	C₂₈H₃₅NO₄
Molecular Weight	437.59 g/mol
Synonyms	17-(Cyclopropylmethyl)-6,7-didehydro-4,5α-epoxy-3,14β-dihydroxy-6,7:2',3'-indolomorphinan; (-)-Oxilorphan; Levallorphan derivative; BNTX; SC-26100; Cyclorphan analog; N-Cyclopropylmethyl-6,7-didehydro-4,5α-epoxy-3,14β-dihydroxymorphinan
EINECS	Contact for details

Quality Control

Our Oxilorphan is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all test results against our stringent in-house specifications. We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.