Description

3-Bromoisothiazolo[4,3-B]Pyridine is a high-purity, heterocyclic organic building block of significant interest in advanced chemical synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Research: Used in the synthesis of new herbicides, fungicides, and insecticides, leveraging its unique heterocyclic structure.
• Material Science: Serves as a precursor for organic electronic materials, including ligands for metal-organic frameworks (MOFs) and organic light-emitting diodes (OLEDs).
• Chemical Biology: Employed as a molecular probe or a tag in bioconjugation chemistry and proteomics research.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Negishi, and Buchwald-Hartwig couplings.
• Ligand Synthesis: Used to prepare novel nitrogen-sulfur containing ligands for catalysis and coordination chemistry.

Basic Information

Product Name	3-Bromoisothiazolo[4,3-B]Pyridine
CAS No.	42242-14-8
Molecular Formula	C6H3BrN2S
Molecular Weight	215.07 g/mol
Synonyms	3-Bromoisothiazolo[4,3-b]pyridine; 3-Bromo-[1,2]thiazolo[4,3-b]pyridine; Isothiazolo[4,3-b]pyridine, 3-bromo-; 3-Bromoisothiazolo(4,3-b)pyridine; 42242-14-8; 3-Bromo-isothiazolo[4,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 3-Bromoisothiazolo[4,3-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.