Description

3-Aminoisothiazolo[4,3-B]Pyridine is a high-purity, heterocyclic organic compound featuring a fused isothiazole and pyridine ring system with a primary amine functional group. This unique molecular architecture makes it a valuable and versatile pharmaceutical intermediate and research chemical for the synthesis of novel bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to develop new drug candidates or functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets, kinase inhibitors, and anti-infective agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive heterocyclic core.
• Material Science Precursor: Serves as a starting material for creating organic ligands in coordination chemistry or for synthesizing specialized polymers and dyes.
• Chemical Biology Probe: Employed in academic and industrial research to study enzyme interactions or as a scaffold for fragment-based drug discovery (FBDD).
• Custom Synthesis: A critical substrate for contract research organizations (CROs) and custom synthesis manufacturers producing tailored compounds for client projects.

Basic Information

Product Name	3-Aminoisothiazolo[4,3-B]Pyridine
CAS No.	42242-13-7
Molecular Formula	C6H5N3S
Molecular Weight	151.19 g/mol
Synonyms	3-Amino[1,2]thiazolo[4,3-b]pyridine; 3-Aminoisothiazolo[4,3-b]pyridine; [1,2]Thiazolo[4,3-b]pyridin-3-amine; 3-Amino-1,2-thiazolo[4,3-b]pyridine; Isothiazolo[4,3-b]pyridin-3-amine; 42242-13-7; 3-Amino-isothiazolo[4,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 3-Aminoisothiazolo[4,3-B]Pyridine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.