Description

2-[[3-(Trifluoromethyl)Phenyl]Amino]-5-Hydroxynicotinic Acid is a high-purity, functionalized nicotinic acid derivative of significant interest in advanced chemical synthesis. This compound matters as a sophisticated pharmaceutical intermediate and research chemical, offering a unique trifluoromethylphenylamino moiety for targeted molecular design. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or inflammatory pathways.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand Synthesis: Serves as a precursor for creating complex ligands used in catalysis and material science applications.
• Chemical Biology Probe Development: Utilized in academic and industrial research to create molecular probes for studying enzyme function and protein interactions.
• Fine Chemical Synthesis: An important intermediate for producing other specialty chemicals with specific fluorinated aromatic properties.

Basic Information

Product Name	2-[[3-(Trifluoromethyl)Phenyl]Amino]-5-Hydroxynicotinic Acid
CAS No.	42240-83-5
Molecular Formula	C13H9F3N2O3
Molecular Weight	298.22 g/mol
Synonyms	5-Hydroxy-2-[[3-(trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic acid; 2-((3-(Trifluoromethyl)phenyl)amino)-5-hydroxynicotinic acid; 2-[(3-Trifluoromethylphenyl)amino]-5-hydroxypyridine-3-carboxylic acid; 2-Amino-5-hydroxy-3-(3-trifluoromethylanilino)pyridine; 42240-83-5; α,α,α-Trifluoro-m-toluidine derivative of 5-hydroxynicotinic acid
EINECS	Contact for details

Quality Control

Our 2-[[3-(Trifluoromethyl)Phenyl]Amino]-5-Hydroxynicotinic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.