Description

2-Hydroxychalcone is a versatile organic compound belonging to the chalcone family, characterized by its distinct α,β-unsaturated ketone structure. This compound serves as a critical synthetic intermediate and a valuable scaffold in medicinal chemistry research due to its bioactive potential. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of various flavonoids and heterocyclic compounds with potential therapeutic applications.
• Medicinal Chemistry Research: Used as a core scaffold for developing novel drug candidates, particularly for screening anti-inflammatory, anticancer, and antioxidant activities.
• Organic Synthesis Building Block: Employed in cyclization reactions to create flavanones, pyrazolines, and other complex molecular structures.
• Biochemical Research: Utilized as a standard or probe in studies investigating enzyme inhibition and biological pathways.
• Material Science Precursor: Investigated for the development of organic semiconductors and photonic materials due to its conjugated system.
• Agrochemical Development: Acts as an intermediate in the research and synthesis of new plant growth regulators or protective agents.

Basic Information

Product Name	2-Hydroxychalcone
CAS No.	42224-53-3
Molecular Formula	C15H12O2
Molecular Weight	224.26 g/mol
Synonyms	2'-Hydroxychalcone; (E)-1-(2-Hydroxyphenyl)-3-phenylprop-2-en-1-one; 2-Hydroxybenzalacetophenone; o-Hydroxychalcone; 1-(2-Hydroxyphenyl)-3-phenyl-2-propen-1-one; NSC 407291; Benzylideneacetophenone, 2'-hydroxy-
EINECS	Contact for details

Quality Control

Our 2-Hydroxychalcone is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-purity standards suitable for research and synthesis. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	88 - 92 °C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.