Description

Ethyl 3H-Spiro[Isobenzofuran-1,4'-Piperidine]-1'-Carboxylate is a high-value, heterocyclic organic compound featuring a unique spirocyclic architecture. This structure makes it a critical advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily sought after by R&D and production teams in the pharmaceutical and fine chemical sectors for the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for novel compound discovery.
• Spirocyclic Compound Synthesis: Serves as a core scaffold for developing new chemical entities with spirocyclic frameworks, which are prized for their three-dimensionality in drug design.
• Fine Chemical Production: Employed in the multi-step synthesis of specialized, high-purity chemicals for research and development.
• Contract Research & Manufacturing (CRAM): Supplied to organizations engaged in custom synthesis and process development for pharmaceutical clients.

Basic Information

Product Name	Ethyl 3H-Spiro[Isobenzofuran-1,4'-Piperidine]-1'-Carboxylate
CAS No.	42191-83-3
Molecular Formula	C15H17NO3
Molecular Weight	259.30 g/mol
Synonyms	Ethyl 1,4-Dihydrospiro[isobenzofuran-1,4'-piperidine]-1'-carboxylate; 1'-Carbethoxy-3H-spiro[isobenzofuran-1,4'-piperidine]; 3H-Spiro[isobenzofuran-1,4'-piperidine]-1'-carboxylic acid ethyl ester; Ethyl 1,4-dihydrospiro[2-benzofuran-1,4'-piperidine]-1'-carboxylate; 42191-83-3; Spiro[isobenzofuran-1(3H),4'-piperidine]-1'-carboxylic acid, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 3H-Spiro[Isobenzofuran-1,4'-Piperidine]-1'-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.