Description

Tetradehydropodophyllotoxin is a key intermediate and derivative of the naturally occurring lignan podophyllotoxin. This compound is of significant interest in pharmaceutical research and development due to its structural relationship to potent bioactive molecules. It serves as a critical building block for the synthesis of novel chemotherapeutic agents and other pharmacologically active compounds. Industries involved in advanced pharmaceutical synthesis, contract research, and fine chemical manufacturing are the primary users of this high-value intermediate.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel anti-cancer agents and other therapeutic compounds.
• Research & Development: Used in academic and industrial laboratories for studying structure-activity relationships (SAR) of podophyllotoxin derivatives.
• Fine Chemical Synthesis: Employed as a specialized building block for creating complex molecular architectures in medicinal chemistry.
• Reference Standard: Utilized as an analytical standard in quality control and method development for related pharmaceutical products.
• Biochemical Research: Applied in studies investigating tubulin polymerization inhibition and other cellular mechanisms.

Basic Information

Product Name	Tetradehydropodophyllotoxin
CAS No.	42123-27-3
Molecular Formula	C22H20O7
Molecular Weight	396.39 g/mol
Synonyms	Deoxypodophyllotoxin; Anthricin; (-)-Deoxypodophyllotoxin; 5,8,8a,9-Tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one; NSC 335153; 4'-Demethyl-4-deoxypodophyllotoxin; 4-Deoxypodophyllotoxin
EINECS	Contact for details

Quality Control

Our Tetradehydropodophyllotoxin is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.