Description

Methyl 3-(4-Bromophenyl)Propiolate is a high-purity organic building block characterized by its brominated aromatic ring and propiolate ester functionality. This compound is of significant value in advanced organic synthesis, serving as a versatile intermediate for constructing complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications such as cross-coupling reactions and the synthesis of bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and potential drug candidates, particularly those requiring a bromoaryl moiety for further functionalization.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where its structure can be incorporated into bioactive molecules.
• Material Science Research: Serves as a monomer or building block for the development of specialized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Sonogashira, Suzuki-Miyaura, and other palladium-catalyzed cross-coupling reactions due to the reactive bromine atom and alkyne group.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and for creating compound libraries in high-throughput screening.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	Methyl 3-(4-Bromophenyl)Propiolate
CAS No.	42122-27-0
Molecular Formula	C10H7BrO2
Molecular Weight	239.07 g/mol
Synonyms	Methyl (4-Bromophenyl)propiolate; 4-Bromophenylpropiolic Acid Methyl Ester; 3-(4-Bromophenyl)-2-propynoic Acid Methyl Ester; Methyl 4-Bromophenylpropiolate; Methyl 3-(p-Bromophenyl)propiolate; Propiolic acid, 3-(4-bromophenyl)-, methyl ester; p-Bromophenylpropiolic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our Methyl 3-(4-Bromophenyl)Propiolate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards. Custom purity grades and analytical packages are available to meet specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.