Description

Diethyl (4-Aminophenyl)Phosphonate is a versatile organophosphorus compound featuring both an amino group and a phosphonate ester moiety. This bifunctional structure makes it a valuable key intermediate in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is essential for chemists and manufacturers engaged in the development of active pharmaceutical ingredients (APIs), crop protection agents, and specialty chemicals where precise molecular construction is critical.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, including kinase inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators that require phosphonate-based structures.
• Ligand and Catalyst Precursor: Serves as a starting material for creating specialized phosphonate-containing ligands used in metal catalysis and coordination chemistry.
• Material Science Research: Employed in the development of flame retardants, specialty polymers, and surface-modifying agents.
• Chemical Biology Probes: Utilized in the design of molecular probes and inhibitors for studying enzymatic processes and signal transduction pathways.

Basic Information

Product Name	Diethyl (4-Aminophenyl)Phosphonate
CAS No.	42022-57-1
Molecular Formula	C10H16NO3P
Molecular Weight	229.21 g/mol
Synonyms	Diethyl P-Aminophenylphosphonate; (4-Aminophenyl)phosphonic Acid Diethyl Ester; Phosphonic Acid, P-(4-Aminophenyl)-, Diethyl Ester; Diethyl 4-Aminobenzene-1-phosphonate; 4-Aminophenylphosphonic Acid Diethyl Ester; Diethyl (p-Aminophenyl)phosphonate; Aminophenylphosphonate Diethyl Ester
EINECS	Contact for details

Quality Control

Our Diethyl (4-Aminophenyl)Phosphonate is produced under stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, and spectroscopic identification (IR, NMR). A detailed Certificate of Analysis (COA) documenting identity, purity, and all relevant specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.