Description

Fenofibric Acid CAS NO 42017-89-0 is the primary active metabolite of fenofibrate, a prominent member of the fibrate class of pharmaceuticals. This compound is a critical intermediate and reference standard in the research, development, and quality control of lipid-regulating medications. It is essential for pharmaceutical manufacturers, analytical laboratories, and research institutions focused on cardiovascular disease treatment and metabolic disorder research.

Application

• Pharmaceutical Active Ingredient (API) Synthesis: Serves as the key active metabolite and a crucial intermediate in the manufacturing of fenofibrate and related fibrate drugs.
• Analytical Reference Standard: Used in High-Performance Liquid Chromatography (HPLC), Liquid Chromatography-Mass Spectrometry (LC-MS), and other analytical methods for the quantification and purity assessment of fenofibrate in drug substances and finished dosage forms.
• Metabolic and Pharmacokinetic Studies: Employed in preclinical and clinical research to study the absorption, distribution, metabolism, and excretion (ADME) profile of fenofibrate.
• Impurity Profiling and Identification: Acts as a known impurity standard to monitor and control the quality of fenofibrate API, ensuring compliance with ICH guidelines.
• Biochemical Research: Utilized in vitro studies to investigate the mechanism of action of fibrates on peroxisome proliferator-activated receptor alpha (PPAR-α) and lipid metabolism pathways.
• Formulation Development: Applied in the development of novel drug delivery systems and dosage forms for improved therapeutic efficacy.

Basic Information

Product Name	Fenofibric Acid
CAS No.	42017-89-0
Molecular Formula	C17H15ClO4
Molecular Weight	318.75 g/mol
Synonyms	2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoic Acid; Fenofibric Acid; Procetofen; Procetofene; Fenofibrate Acid; Lipanthyl Acid; Isopropyl 2-[p-(p-Chlorobenzoyl)phenoxy]-2-methylpropionate Acid; FENOFIBRIC ACID (FENOFIBRATE METABOLITE)
EINECS	Contact for details

Quality Control

Our Fenofibric Acid is produced and tested under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including identification, assay, and impurity profiling via advanced techniques like HPLC and LC-MS to ensure it meets high-purity standards suitable for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with specified specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.