Description

2,4,6-Tris(4-Fluorophenyl)Pyridine is a specialized fluorinated heterocyclic compound that serves as a critical building block in advanced materials science and pharmaceutical research. Its unique molecular architecture, featuring a central pyridine ring symmetrically substituted with fluorinated phenyl groups, makes it a valuable precursor for synthesizing complex organic frameworks and functional materials. This high-purity intermediate is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries for applications requiring precise molecular control and fluorination effects.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology, where fluorine substitution can enhance metabolic stability and bioavailability.
• Ligand & Catalyst Precursor: Used in the synthesis of sophisticated nitrogen-containing ligands for transition metal catalysis, enabling more efficient and selective cross-coupling reactions in fine chemical manufacturing.
• Organic Electronic Materials: Serves as a core structure for developing electron-transport materials (ETMs), host materials, and emitters in organic light-emitting diodes (OLEDs) and perovskite solar cells due to its electron-deficient pyridine core and fluorinated periphery.
• Agrochemical Research: Employed as a building block for novel herbicides, fungicides, and plant growth regulators, leveraging the fluorine atoms to influence lipophilicity and target binding.
• Advanced Polymer Monomer: Incorporated into high-performance polymers and polyimides to impart thermal stability, chemical resistance, and specific optical properties for aerospace and microelectronics applications.
• Metal-Organic Framework (MOF) Synthesis: Acts as a functionalized linker molecule for constructing porous coordination polymers with tailored pore environments for gas storage, separation, or sensing.

Basic Information

Product Name	2,4,6-Tris(4-Fluorophenyl)Pyridine
CAS No.	41855-53-2
Molecular Formula	C23H14F3N
Molecular Weight	361.36 g/mol
Synonyms	2,4,6-Tri(4-fluorophenyl)pyridine; 2,4,6-Tris(p-fluorophenyl)pyridine; Pyridine, 2,4,6-tris(4-fluorophenyl)-; 2,4,6-Tris(4-fluorophenyl)pyridin; Tris(4-fluorophenyl)pyridine; 4-Fluoro-2,4,6-triphenylpyridine (related isomer); TFP (common abbreviation)
EINECS	Contact for details

Quality Control

Our 2,4,6-Tris(4-Fluorophenyl)Pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment, NMR (1H, 13C, 19F) for structural confirmation, and mass spectrometry for identity verification. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment. We support cGMP-grade production for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to prevent any potential moisture uptake. For long-term storage (>12 months), consider storage under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.