Description

trans-3-Bromodihydro-3,5-Dimethylfuran-2(3H)-One is a versatile brominated lactone building block of significant interest in advanced organic synthesis. Its unique structure, featuring a reactive bromine atom adjacent to a carbonyl group, makes it a valuable precursor for constructing complex heterocyclic frameworks and chiral intermediates. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of potential drug candidates, particularly for molecules containing functionalized furanone or lactone moieties.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its reactive halogen for further functionalization.
• Organic Synthesis Building Block: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitution reactions to introduce complex side chains.
• Material Science Research: Investigated as a monomer or precursor for the synthesis of specialized polymers and functional materials with unique properties.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in asymmetric synthesis and the development of new synthetic pathways.

Basic Information

Product Name	trans-3-Bromodihydro-3,5-Dimethylfuran-2(3H)-One
CAS No.	41788-51-6
Molecular Formula	C6H9BrO2
Molecular Weight	193.04 g/mol
Synonyms	3-Bromo-3,5-dimethyldihydrofuran-2(3H)-one; 3-Bromo-5-methyl-5H-furan-2-one; trans-3-Bromo-3,5-dimethyl-2(3H)-furanone; 3-Bromo-3,5-dimethyl-dihydro-furan-2-one; 3-Bromodihydro-3,5-dimethyl-2(3H)-furanone; 3-Bromo-3,5-dimethyltetrahydrofuran-2-one; (3R*,5R*)-3-Bromo-3,5-dimethyldihydrofuran-2(3H)-one (racemic mixture)
EINECS	Contact for details

Quality Control

Our trans-3-Bromodihydro-3,5-Dimethylfuran-2(3H)-One is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.