Description

(E)-1-(4-Chlorophenyl)-3-(4-Methylphenyl)-2-Propen-1-One is a high-purity chalcone derivative, a key organic intermediate valued for its defined stereochemistry and functional group reactivity. This compound is essential for researchers and manufacturers requiring a precise building block for synthesizing more complex molecules in pharmaceutical and agrochemical development. It is primarily utilized by R&D chemists and process development teams in the fine chemical, life science, and advanced material sectors.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting anti-inflammatory, anticancer, or antimicrobial pathways.
• Agrochemical Research: Used as a scaffold for developing new active ingredients for crop protection products, such as fungicides or herbicides.
• Organic Synthesis Building Block: The α,β-unsaturated ketone (enone) moiety is a versatile functional group for Michael additions, cyclizations, and other C-C bond-forming reactions.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating polymers with specific optical or electronic properties.
• Chemical Biology Probe: Utilized in academic and industrial research to study biological processes or as a fluorescent tag precursor.

Basic Information

Product Name	(E)-1-(4-Chlorophenyl)-3-(4-Methylphenyl)-2-Propen-1-One
CAS No.	41564-66-3
Molecular Formula	C16H13ClO
Molecular Weight	256.73 g/mol
Synonyms	(E)-1-(4-Chlorophenyl)-3-(p-tolyl)prop-2-en-1-one; 4'-Chloro-4-methylchalcone; (E)-3-(4-Methylphenyl)-1-(4-chlorophenyl)-2-propen-1-one; p-Chloro-p'-methylchalcone; 1-(4-Chlorophenyl)-3-(4-methylphenyl)-2-propen-1-one; 2-Propen-1-one, 1-(4-chlorophenyl)-3-(4-methylphenyl)-, (E)-; 41564-66-3
EINECS	Contact for details

Quality Control

Our (E)-1-(4-Chlorophenyl)-3-(4-Methylphenyl)-2-Propen-1-One is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	108 - 112 °C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.