Description

4-Bromo-2-(Trifluoromethyl)Phenyl Isocyanate is a specialized aromatic isocyanate building block, distinguished by the presence of bromine and trifluoromethyl substituents on the phenyl ring. This compound is highly valued for its role in synthesizing advanced chemical intermediates, particularly in the development of pharmaceuticals and agrochemicals. It is primarily sought by research chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing novel ureas, carbamates, and other functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the bromine and trifluoromethyl groups confer specific biological activity and stability.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the development of specialty polyurethanes and polymers with unique thermal and chemical resistance properties.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for transition metal catalysis and organocatalysts used in asymmetric synthesis.
• Material Science Research: Utilized in the synthesis of advanced organic materials, including liquid crystals and organic semiconductors.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	4-Bromo-2-(Trifluoromethyl)Phenyl Isocyanate
CAS No.	41513-02-4
Molecular Formula	C8H3BrF3NO
Molecular Weight	266.02 g/mol
Synonyms	1-Bromo-4-isocyanato-2-(trifluoromethyl)benzene; 2-Trifluoromethyl-4-bromophenyl isocyanate; 4-Bromo-α,α,α-trifluoro-o-tolyl isocyanate; Isocyanic acid, 4-bromo-2-(trifluoromethyl)phenyl ester; (4-Bromo-2-trifluoromethylphenyl)isocyanate; 4-Bromo-2-trifluoromethylphenyl isocyanate
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-(Trifluoromethyl)Phenyl Isocyanate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.