Description

2-Bromo-4,6-difluoropyridine is a high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents, makes it an exceptionally versatile intermediate for introducing functional complexity into target molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex heterocyclic cores in drug discovery, particularly for candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the difluoropyridine moiety enhances biological activity and metabolic stability.
• Ligand & Catalyst Preparation: Serves as a precursor for synthesizing specialized nitrogen-containing ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers and light-emitting components, due to its electron-deficient aromatic system.
• Custom Chemical Synthesis: Provides a versatile handle for further functionalization via metal-catalyzed cross-coupling (e.g., Suzuki, Stille) or nucleophilic aromatic substitution reactions.

Basic Information

Product Name	2-Bromo-4,6-difluoropyridine
CAS No.	41404-63-1
Molecular Formula	C5H2BrF2N
Molecular Weight	193.98 g/mol
Synonyms	2-Bromo-4,6-difluoropyridine; 4,6-Difluoro-2-bromopyridine; Pyridine, 2-bromo-4,6-difluoro-; 2-Bromo-4,6-difluoro-pyridin; 2-Br-4,6-F2-Py
EINECS	Contact for details

Quality Control

Our 2-Bromo-4,6-difluoropyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to verify identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support cGMP and ISO 9001 compliant manufacturing for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination. Store away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.