Description

Diethyl 2-[(2-Chloroacetyl)Amino]Propanedioate is a key synthetic intermediate in organic chemistry, valued for its bifunctional reactive sites. This compound is essential for facilitating the construction of complex heterocyclic and peptide-like structures in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical and active pharmaceutical ingredient (API) manufacturing sectors.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of various drug candidates, particularly those containing heterocyclic cores like imidazoles or hydantoins.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging its reactive chloroacetyl and ester groups.
• Peptidomimetic Research: Serves as a scaffold for creating modified amino acid derivatives and peptide analogs in medicinal chemistry.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for specialty chemicals requiring specific functional group transformations.
• Academic & Industrial R&D: A versatile reagent for methodological development in organic synthesis and new reaction pathway exploration.

Basic Information

Product Name	Diethyl 2-[(2-Chloroacetyl)Amino]Propanedioate
CAS No.	41394-71-2
Molecular Formula	C9H14ClNO5
Molecular Weight	251.66 g/mol
Synonyms	Diethyl (2-Chloroacetamido)malonate; 2-[(2-Chloroacetyl)amino]propanedioic acid diethyl ester; Diethyl N-(chloroacetyl)aminomalonate; N-(Chloroacetyl)aminomalonic acid diethyl ester; Chloroacetamidomalonic ester; CAAM; Aminomalonic acid diethyl ester N-chloroacetyl derivative
EINECS	Contact for details

Quality Control

Our Diethyl 2-[(2-Chloroacetyl)Amino]Propanedioate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request, supporting your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.