Description

2-Chloro-5-Methylthio-Pyridine is a versatile halogenated heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in the strategic positioning of the chloro and methylthio substituents, which enable selective functionalization for constructing complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and anti-infective agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, where the pyridine core contributes to biological activity.
• Ligand and Catalyst Precursor: Serves as a starting material for the synthesis of specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or molecular components for OLEDs.
• Custom Chemical Synthesis: A valuable building block for contract research organizations (CROs) and CDMOs performing custom synthesis and scale-up services.

Basic Information

Product Name	2-Chloro-5-Methylthio-Pyridine
CAS No.	41288-94-2
Molecular Formula	C6H6ClNS
Molecular Weight	159.63 g/mol
Synonyms	2-Chloro-5-(methylthio)pyridine; 5-(Methylthio)-2-chloropyridine; 2-Chloro-5-methylsulfanylpyridine; 2-Chloro-5-methylmercaptopyridine; 2-Chloro-5-(methylsulfanyl)pyridine; Pyridine, 2-chloro-5-(methylthio)-; 41288-94-2
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Methylthio-Pyridine is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.