Description

4-Methylumbelliferyl-4-Trimethylammonium Cinnamate is a specialized cationic cinnamate derivative, primarily valued as a key synthetic intermediate and a chromogenic substrate for enzymatic assays. Its structure combines a fluorescent umbelliferone core with a quaternary ammonium group, making it highly relevant for advanced biochemical research and diagnostic applications. This compound is essential for researchers and manufacturers in the life sciences, pharmaceutical development, and diagnostic reagent sectors.

Application

• Enzymatic Substrate: Acts as a chromogenic and fluorogenic substrate for the detection and kinetic study of specific hydrolases and esterases in biochemical assays.
• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of more complex drug candidates and prodrugs, particularly those targeting cellular delivery.
• Diagnostic Reagent Manufacturing: Used in the formulation of test kits for clinical diagnostics and research to measure enzyme activity.
• Biochemical Research: Employed in mechanistic studies of enzyme inhibition and as a tool compound in cell biology to probe membrane-associated processes.
• Fluorescence-Based Sensing: Utilized in the development of fluorescent probes and sensors due to its umbelliferyl moiety, which exhibits favorable fluorescence properties.

Basic Information

Product Name	4-Methylumbelliferyl-4-Trimethylammonium Cinnamate
CAS No.	41236-02-6
Molecular Formula	C23H24NO5+ (typically as a salt, e.g., chloride)
Molecular Weight	394.44 g/mol (for free cation)
Synonyms	4-MU-TMA Cinnamate; 4-Methylumbelliferyl 4-(Trimethylammonio)cinnamate; 7-Hydroxy-4-methylcoumarin-4-trimethylammonium cinnamate ester; 4-Trimethylammoniocinnamic acid 4-methylumbelliferyl ester; TMA-Cinnamate-4-MU; 4-Methylumbelliferyl-4-(N,N,N-trimethylammonium)cinnamate; (E)-4-(Trimethylammonio)cinnamic acid 4-methyl-2-oxo-2H-chromen-7-yl ester
EINECS	Contact for details

Quality Control

Our 4-Methylumbelliferyl-4-Trimethylammonium Cinnamate is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light) and may be hygroscopic; therefore, the container should be kept tightly sealed in a desiccated environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.