Description

Methyl (R)-(+)-3-(tert-Butyldimethylsilyloxy)-5-Oxo-1-Cyclopentene-1-Heptanoate is a high-value, chiral synthetic intermediate characterized by its protected hydroxyl and ketone functionalities. This compound matters for its critical role in the stereoselective synthesis of complex bioactive molecules, offering a key chiral building block for advanced pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing prostaglandin analogs and other chiral targets.

Application

• Key chiral intermediate in the total synthesis of prostaglandins and their analogs.
• Advanced building block for pharmaceutical research targeting inflammation, cardiovascular, and ocular diseases.
• Stereoselective synthesis of other complex natural products and bioactive compounds.
• Process chemistry for scaling up the production of chiral active pharmaceutical ingredients (APIs).
• Agrochemical research for developing novel, stereospecific active ingredients.
• Academic and institutional research in organic methodology and asymmetric synthesis.

Basic Information

Product Name	Methyl (R)-(+)-3-(tert-Butyldimethylsilyloxy)-5-Oxo-1-Cyclopentene-1-Heptanoate
CAS No.	41138-69-6
Molecular Formula	C19H36O4Si
Molecular Weight	356.58 g/mol
Synonyms	(R)-Methyl 3-((tert-Butyldimethylsilyl)oxy)-5-oxo-1-cyclopentene-1-heptanoate; Methyl (3R)-3-[(1,1-Dimethylethyl)dimethylsilyl]oxy-5-oxo-1-cyclopentene-1-heptanoate; (R)-3-(tert-Butyldimethylsiloxy)-5-oxo-1-cyclopentene-1-heptanoic Acid Methyl Ester; Prostaglandin Intermediate; PGF2α Synthetic Intermediate; TBS-protected Prostaglandin Intermediate; Chiral Cyclopentenone Ester
EINECS	Contact for details

Quality Control

Our Methyl (R)-(+)-3-(tert-Butyldimethylsilyloxy)-5-Oxo-1-Cyclopentene-1-Heptanoate is produced under strict quality management systems to ensure batch-to-batch consistency and high chiral purity for research and development applications. Certificates of Analysis (COA) are provided with each batch, detailing specifications for identity, purity, and enantiomeric excess. We support compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label or COA. This material is light-sensitive and should be handled under an inert atmosphere when appropriate to minimize degradation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.