Description

Isopropyl Trifluoromethanesulfonate is a specialized organosulfur reagent, widely recognized for its potent triflylating and alkylating properties. Its high reactivity makes it a critical intermediate for constructing complex molecules in advanced synthetic chemistry. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries, where it facilitates key transformations such as esterification and the introduction of the isopropyl group under mild conditions.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing the isopropyl or trifluoromethanesulfonate moiety.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that require specific fluorinated or sulfonated structures.
• Polymer & Materials Science: Serves as a monomer or modifying agent in the creation of specialty polymers, including fluorinated polymers and high-performance resins.
• Organic Synthesis Reagent: Employed as a powerful triflylating agent to activate alcohols and phenols, and as an alkylating agent in C-O and C-N bond formation reactions.
• Ligand & Catalyst Preparation: Utilized in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis and cross-coupling reactions.
• Fine Chemical Production: Integral to the multistep synthesis of complex fine chemicals, flavors, and fragrances.

Basic Information

Product Name	Isopropyl Trifluoromethanesulfonate
CAS No.	41029-44-1
Molecular Formula	C4H7F3O3S
Molecular Weight	192.16 g/mol
Synonyms	Isopropyl Triflate; Trifluoromethanesulfonic Acid Isopropyl Ester; 2-Propanol, 1,1,1-trifluoro-N-(1-methylethyl)methanesulfonate; Isopropyl Trifluoromethanesulphonate; Isopropyl Triflate Reagent; 1-Methylethyl Trifluoromethanesulfonate; 2-Propyl Trifluoromethanesulfonate; TFI
EINECS	Contact for details

Quality Control

Our Isopropyl Trifluoromethanesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.