Description

Diethyl Isocyanomethylphosphonate is a specialized organophosphorus compound that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring both phosphonate and isocyanide functional groups, makes it a versatile reagent for constructing complex molecular architectures. This high-value intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those with phosphorus-containing bioactive molecules.
• Agrochemical Synthesis: Building block for creating advanced pesticides, herbicides, and plant growth regulators.
• Ligand and Catalyst Development: Used in the preparation of specialized phosphine-based ligands for transition metal catalysis.
• Peptide Mimetics and Isosteres: Employed in medicinal chemistry to create phosphonate-based peptide analogs and transition state inhibitors.
• Material Science Research: Intermediate for synthesizing functionalized polymers and advanced materials with specific properties.
• Chemical Biology Probes: Utilized in the development of activity-based probes and other tools for studying biological processes.

Basic Information

Product Name	Diethyl Isocyanomethylphosphonate
CAS No.	41003-94-5
Molecular Formula	C7H14NO3P
Molecular Weight	191.16 g/mol
Synonyms	Diethyl (isocyanomethyl)phosphonate; (Isocyanomethyl)phosphonic Acid Diethyl Ester; Diethyl Phosphonoacetonitrile N-Oxide?; Diethyl P-isocyanomethylphosphonate; Phosphonic acid, P-(isocyanomethyl)-, diethyl ester; NSC 163063; Isocyanomethanephosphonic acid diethyl ester
EINECS	Contact for details

Quality Control

Every batch of Diethyl Isocyanomethylphosphonate is manufactured and tested under strict quality management protocols to ensure consistency and purity for demanding synthetic applications. Our products undergo rigorous analytical testing, including NMR, HPLC, and GC-MS, to verify identity and quantify purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizing agents. Recommended storage temperature is 2-8°C for extended stability. The container must be kept tightly sealed due to moisture sensitivity and potential volatility.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.