Description

2-Amino-3-Hydroxy-5-Chloropyridine is a versatile heterocyclic building block of significant importance in advanced organic synthesis. Its unique structure, featuring amino, hydroxy, and chloro substituents, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is essential for research and development chemists and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key precursor for active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly for central nervous system (CNS) agents, antimicrobials, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands used in catalysis and metal complexation.
• Material Science Research: Employed in the development of organic electronic materials, dyes, and photoactive compounds.
• Chemical Research & Development: A valuable building block for academic and industrial R&D exploring new heterocyclic chemistry and reaction pathways.

Basic Information

Product Name	2-Amino-3-Hydroxy-5-Chloropyridine
CAS No.	40966-87-8
Molecular Formula	C5H5ClN2O
Molecular Weight	144.56 g/mol
Synonyms	5-Chloro-3-hydroxy-2-pyridinamine; 5-Chloro-2-amino-3-pyridinol; 5-Chloro-3-pyridinol-2-amine; 2-Amino-5-chloro-3-pyridinol; 3-Hydroxy-5-chloro-2-aminopyridine; 5-Chloro-2,3-diaminopyridine (common misnomer); 5-Chloro-3-hydroxypyridin-2-amine
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Hydroxy-5-Chloropyridine is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.