Description

4-Bromo-3-Picoline Hcl is a halogenated pyridine derivative, specifically the hydrochloride salt of 4-bromo-3-methylpyridine, serving as a versatile and high-value building block in advanced organic synthesis. Its core value lies in providing a reactive bromine substituent and a basic nitrogen center, enabling precise molecular construction for complex target molecules. This intermediate is critically needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Building block for creating advanced herbicides, fungicides, and insecticides that require specific halogenated pyridine motifs.
• Ligand and Catalyst Development: Used to prepare specialized pyridine-based ligands for transition metal catalysis and coordination chemistry.
• Material Science Research: Intermediate in the production of organic electronic materials, such as charge-transport layers or metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Serves as a tagging or linking agent in the development of biochemical probes and affinity labels.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke, multi-step synthetic routes.

Basic Information

Product Name	4-Bromo-3-Picoline Hcl
CAS No.	40899-37-4
Molecular Formula	C6H7BrClN
Molecular Weight	208.48 g/mol
Synonyms	4-Bromo-3-methylpyridine hydrochloride; 3-Methyl-4-bromopyridine hydrochloride; 4-Bromo-3-picoline hydrochloride; 4-Bromo-3-methylpyridinium chloride; 40899-37-4; 4-Br-3-pic·HCl
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Picoline Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed results from HPLC, NMR, and GC-MS. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.