Description

5-Chloro-2-(trifluoromethyl)-3H-imidazo[4,5-b]pyridine is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core structure, featuring both an imidazopyridine scaffold and halogen/trifluoromethyl substituents, makes it a critical intermediate for developing novel bioactive molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides, leveraging the bioactivity of the imidazopyridine core.
• Chemical Biology Probe: Acts as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Material Science Research: Investigated as a building block for advanced organic electronic materials due to its electron-deficient aromatic system.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects and library production.

Basic Information

Product Name	5-Chloro-2-(trifluoromethyl)-3H-imidazo[4,5-b]pyridine
CAS No.	40851-96-5
Molecular Formula	C7H3ClF3N3
Molecular Weight	221.57 g/mol
Synonyms	5-Chloro-2-(trifluoromethyl)-1H-imidazo[4,5-b]pyridine; 5-Chloro-2-(trifluoromethyl)imidazo[4,5-b]pyridine; 3H-Imidazo[4,5-b]pyridine, 5-chloro-2-(trifluoromethyl)-; 40851-96-5; 5-Chloro-2-trifluoromethyl-3H-imidazo[4,5-b]pyridine
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-(trifluoromethyl)-3H-imidazo[4,5-b]pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.