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21,23-Epoxy-3β,12β,23-Tris[(Trimethylsilyl)Oxy]-24-Nor-5β-Chola-20,22-Dien-14β-Ol CAS NO 40837-85-2


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CAS No.:40837-85-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

21,23-Epoxy-3β,12β,23-Tris[(Trimethylsilyl)Oxy]-24-Nor-5β-Chola-20,22-Dien-14β-Ol is a high-purity, advanced steroidal intermediate characterized by its unique epoxy and silyl-protected functional groups. This compound is critical for the synthesis of complex bioactive molecules, offering precise structural control in multi-step organic transformations. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel steroid-based therapeutics and fine chemical synthesis.

Application

  • Pharmaceutical Intermediate: A key building block in the research and development of novel steroid-derived drugs and active pharmaceutical ingredients (APIs).
  • Organic Synthesis Reagent: Used in advanced synthetic chemistry for constructing complex steroidal frameworks and introducing specific functional groups.
  • Biochemical Research: Serves as a precursor or standard in metabolic pathway studies and enzyme interaction research related to steroid hormones.
  • Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals for academic and industrial laboratories.
  • Process Development: Used in scaling up synthetic routes and optimizing production processes for steroidal compounds.

Basic Information

Item Details
Product Name 21,23-Epoxy-3β,12β,23-Tris[(Trimethylsilyl)Oxy]-24-Nor-5β-Chola-20,22-Dien-14β-Ol
CAS No. 40837-85-2
Molecular Formula C32H58O5Si3
Molecular Weight 607.07 g/mol
Synonyms 21,23-Epoxy-3β,12β,23-tris[(trimethylsilyl)oxy]-24-nor-5β-chola-20,22-dien-14β-ol; 3β,12β,23-Tris-O-(trimethylsilyl)-21,23-epoxy-24-nor-5β-chola-20,22-dien-14β-ol; 24-Norchola-20,22-dien-14β-ol, 21,23-epoxy-3β,12β,23-tris[(trimethylsilyl)oxy]-, (5β)-; Steroid TMS ether intermediate; Silylated steroidal epoxy intermediate
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Quality Control

Our 21,23-Epoxy-3β,12β,23-Tris[(Trimethylsilyl)Oxy]-24-Nor-5β-Chola-20,22-Dien-14β-Ol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item Specification
Appearance White to off-white powder or crystalline solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 1.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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