Description

Methyl 4-Iodo-1-Methyl-1H-Pyrrole-2-Carboxylate is a high-purity, functionalized pyrrole derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile halogenated heterocyclic scaffold for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the pyrrole core for bioactivity.
• Material Science: Serves as a monomer or functionalizing agent in the creation of conductive polymers, organic semiconductors, and advanced organic frameworks (MOFs/COFs).
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Sonogashira) to form carbon-carbon bonds.
• Chemical Biology: Employed as a probe or labeling agent in biochemical research due to its reactive halogen and ester functionality.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and small-scale GMP batches.

Basic Information

Product Name	Methyl 4-Iodo-1-Methyl-1H-Pyrrole-2-Carboxylate
CAS No.	40740-42-9
Molecular Formula	C7H8INO2
Molecular Weight	265.05 g/mol
Synonyms	1-Methyl-4-iodo-1H-pyrrole-2-carboxylic acid methyl ester; Methyl 1-methyl-4-iodopyrrole-2-carboxylate; 4-Iodo-1-methyl-1H-pyrrole-2-carboxylic acid methyl ester; 1-Methyl-4-iodopyrrole-2-carboxylic acid methyl ester; 40740-42-9; Methyl 4-iodo-1-methylpyrrole-2-carboxylate; 1H-Pyrrole-2-carboxylic acid, 4-iodo-1-methyl-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 4-Iodo-1-Methyl-1H-Pyrrole-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications in research and pre-clinical development, where material integrity is paramount.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.