Description

3-Methyl-1H-Pyrazole-4-Carboxylic Acid is a versatile heterocyclic building block and organic intermediate of significant importance in advanced chemical synthesis. Its core value lies in its functionalized pyrazole ring, which serves as a key scaffold for constructing more complex molecules with targeted biological or material properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the pyrazole moiety contributes to biological activity.
• Ligand and Catalyst Development: Serves as a chelating agent or precursor for ligands in coordination chemistry and catalysis, useful in organic transformations and material science.
• Material Science Research: Employed in the creation of organic semiconductors, metal-organic frameworks (MOFs), and polymers with specific electronic or structural properties.
• Chemical Biology & Proteomics: Acts as a building block for activity-based probes and molecular tags used in studying enzyme function and protein interactions.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom chemical synthesis services, enabling the production of bespoke compounds for R&D and pilot-scale projects.

Basic Information

Product Name	3-Methyl-1H-Pyrazole-4-Carboxylic Acid
CAS No.	40704-11-8
Molecular Formula	C5H6N2O2
Molecular Weight	126.11 g/mol
Synonyms	3-Methyl-1H-pyrazole-4-carboxylic acid; 3-Methyl-4-pyrazolecarboxylic acid; 4-Carboxy-3-methylpyrazole; 3-Methylpyrazole-4-carboxylic acid; 1H-Pyrazole-4-carboxylic acid, 3-methyl-; 3-Methyl-1H-4-pyrazolecarboxylic acid; 3-Methyl-4-carboxypyrazole; NSC 163022
EINECS	Contact for details

Quality Control

Our 3-Methyl-1H-Pyrazole-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed after opening to minimize exposure to atmospheric humidity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.